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Key Documents

AV32586

Sigma-Aldrich

Anti-HIPK2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Homeodomain interacting protein kinase 2, Anti-PRO0593

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

120 kDa

species reactivity

guinea pig, rat, dog, human, horse, mouse

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_073577

UniProt accession no.

Q9H2X6

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HIPK2(28996)

Immunogen

Synthetic peptide directed towards the middle region of Human HIPK2

Biochem/physiol Actions

HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.

Sequence

Synthetic peptide located within the following region: MWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTR

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Andreas Möller et al.
Cancer research, 63(15), 4310-4314 (2003-08-09)
Here we demonstrate that endogenous human homeodomain-interacting protein kinase (HIPK) 2 and the highly homologous kinase HIPK3 are found in a novel subnuclear domain, the HIPK domains. These are distinct from other subnuclear structures such as Cajal bodies and nucleoli
Chie Kanei-Ishii et al.
Genes & development, 18(7), 816-829 (2004-04-15)
The c-myb proto-oncogene product (c-Myb) regulates both the proliferation and apoptosis of hematopoietic cells by inducing the transcription of a group of target genes. However, the biologically relevant molecular mechanisms that regulate c-Myb activity remain unclear. Here we report that

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