A5686

Arg-Gly-Glu-Ser acetate salt

≥95% (HPLC)

• Empirical Formula (Hill Notation): C₁₆H₂₉N₇O₈
• CAS Number: 159002-32-1
• Molecular Weight: 447.44
• MDL number: MFCD00133106
• UNSPSC Code: 12352202
• PubChem Substance ID: 329770831
• NACRES: NA.32

Properties

• biological source: synthetic (organic)
• assay: ≥95% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: CC(O)=O.N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O
• InChI: 1S/C16H29N7O8.C2H4O2/c17-8(2-1-5-20-16(18)19)13(28)21-6-11(25)22-9(3-4-12(26)27)14(29)23-10(7-24)15(30)31;1-2(3)4/h8-10,24H,1-7,17H2,(H,21,28)(H,22,25)(H,23,29)(H,26,27)(H,30,31)(H4,18,19,20);1H3,(H,3,4)/t8-,9-,10-;/m0./s1
• InChI key: SALKOFBHHIHLSW-PUBMXKGKSA-N
• Gene Information: human ... FN1(2335) ; mouse ... FN1(14268) ; rat ... FN1(25661)

Description

Amino Acid Sequence

Arg-Gly-Glu-Ser

Application

Arg-Gly-Glu-Ser acetate salt has been used:

• as an integrin blocking peptide to study its effects on ciliary neurotrophic factor (CNTF) regulation in astroglioma cells
• as a control peptide to study its effects on the binding of patient IgG to integrin αvβ6
• as an integrin inhibitor peptide to study its effects on cell adhesion in Capsaspora owczarzaki cells

Biochem/physiol Actions

Arg-Gly-Glu-Ser peptide acts as an integrin-blocking peptide.

Inhibitor of platelet aggregation

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)