A3903

1-Aminocyclopropanecarboxylic acid

≥98% (TLC), powder, NMDA agonist

• Synonym(s): ACC, ACPC
• Empirical Formula (Hill Notation): C₄H₇NO₂
• CAS Number: 22059-21-8
• Molecular Weight: 101.10
• Beilstein/REAXYS Number: 2076413
• MDL number: MFCD00009944
• UNSPSC Code: 12352209
• PubChem Substance ID: 24890826
• NACRES: NA.32

Properties

• product name: 1-Aminocyclopropanecarboxylic acid, ≥98% (TLC), powder
• Quality Level: 200
• assay: ≥98% (TLC)
• form: powder
• storage condition: (Keep container tightly closed in a dry and well-ventilated place.; Keep in a dry place.)
• color: white
• mp: 229-231 °C (lit.)
• solubility: water: 49.00-51.00 mg/mL, clear, colorless
• SMILES string: NC1(CC1)C(O)=O
• InChI: 1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
• InChI key: PAJPWUMXBYXFCZ-UHFFFAOYSA-N
• Gene Information: human ... NARG2(79664) ; mouse ... NARG2(93697) ; rat ... LOC686240(686240) , NARG2(691379)

Description

General description

Research area: Cell Signaling

1-Aminocyclopropanecarboxylic acid (ACC) is a non-proteinogenic amino acid and is a member of 1-aminocycloalkanecarboxylic acids.

Application

1-Aminocyclopropanecarboxylic acid (ACC) has been used as a substrate for determining ACC deaminase activity to study the plant growth-promoting characteristics of endophytic isolates obtained from Pteris vittata roots, cucurbit seeds. It has also been used as an ethylene precursor to study the effect of high ethylene concentration on lateral root density (LRD) in sorghum brown midrib (bmr) mutants.

Biochem/physiol Actions

1-Aminocyclopropanecarboxylic acid (ACC) is a partial agonist acting at the N-methyl-D-aspartate (NMDA) receptor glycine modulatory site. ACC serves as a bio-synthetic precursor for the plant hormone ethylene. Therefore, it also plays a vital role in plant development. ACC exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves