Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

89270

Sigma-Aldrich

Thymidine

≥99.0% (HPLC)

Synonym(s):

1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H14N2O5
CAS Number:
50-89-5
Molecular Weight:
242.23
Beilstein/REAXYS Number:
89285
EC Number:
200-070-4
MDL number:
MFCD00006537
UNSPSC Code:
41106305
PubChem Substance ID:
329769717
NACRES:
NA.51

biological source

synthetic

Quality Level

200

assay

≥99.0% (HPLC)

form

powder

optical activity

[α]20/D +19±1°, c = 1% in H2O

mp

185-190 °C
186-188 °C (lit.)

solubility

hot water: 1 g/10 mL

SMILES string

CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

InChI key

IQFYYKKMVGJFEH-XLPZGREQSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Thymidine has been used:
  • to culture human fibroblast cell lines.
  • in in vitro wound healing assay.
  • to culture various cancer cell lines.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Cédric F Invernizzi et al.
The Journal of antimicrobial chemotherapy, 68(10), 2192-2196 (2013-06-12)
We recently reported the preferential selection of the K65R resistance mutation in subtype C HIV-1 compared with subtype B and showed the underlying mechanism to be dependent on subtype C-specific silent nucleotide polymorphisms, i.e. genomic mutations that change the genotype
Edward J Gane et al.
Gastroenterology, 146(1), 138-146 (2013-09-27)
There is a close relationship between chronic hepatitis B virus infection and chronic renal disease. We analyzed changes in renal function using different markers of glomerular filtration rate (GFR) in multiple studies of telbivudine treatment of patients with chronic hepatitis
Yee Suan Poo et al.
PLoS neglected tropical diseases, 8(12), e3354-e3354 (2014-12-05)
The recent epidemic of the arthritogenic alphavirus, chikungunya virus (CHIKV) has prompted a quest to understand the correlates of protection against virus and disease in order to inform development of new interventions. Herein we highlight the propensity of CHIKV infections
Anne P Bouvy et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(8), 1587-1597 (2014-04-29)
To evaluate the influence of induction therapy on Tregs we investigated their origin, kinetics and function in kidney transplant patients after treatment with T-cell depleting rabbit antithymocyte globulin (rATG) or IL-2 receptor antagonist basiliximab. Flow cytometry was used to study
Michael V Airola et al.
PloS one, 9(8), e105830-e105830 (2014-08-22)
Acid sphingomyelinase (aSMase) is a human enzyme that catalyzes the hydrolysis of sphingomyelin to generate the bioactive lipid ceramide and phosphocholine. ASMase deficiency is the underlying cause of the genetic diseases Niemann-Pick Type A and B and has been implicated
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service