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80486

Sigma-Aldrich

Hyaluronic acid sodium salt from Streptococcus equi

mol wt 1,250,000-1,500,000

Synonym(s):

Sodium hyaluronate

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About This Item

CAS Number:
9067-32-7
MDL number:
MFCD01773053
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

(Streptococcus equi)

form

powder

mol wt

1,250,000-1,500,000

color

white

solubility

water: ~5 g/L

suitability

conforms to structure for Infrared spectrum

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI key

YWIVKILSMZOHHF-QJZPQSOGSA-N

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Application

suitable as substrate for hyaluronidase

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Glenn D Prestwich
Journal of controlled release : official journal of the Controlled Release Society, 155(2), 193-199 (2011-04-26)
The development of injectable and biocompatible vehicles for delivery, retention, growth, and differentiation of stem cells is of paramount importance for regenerative medicine. For cell therapy and the development of clinical combination products, we created a hyaluronan (HA)-based synthetic extracellular
David T Beattie et al.
Frontiers in pharmacology, 2, 25-25 (2011-06-21)
This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT(4) receptor agonist. TD-8954 had high affinity (pK(i) = 9.4) for human recombinant 5-HT(4(c)) (h5-HT(4(c))) receptors, and selectivity (>2,000-fold) over all other 5-hydroxytryptamine (5-HT) receptors
Liming Bian et al.
Biomaterials, 32(27), 6425-6434 (2011-06-10)
Mesenchymal stem cells (MSCs) are being recognized as a viable cell source for cartilage repair and members of the transforming growth factor-beta (TGF-β) superfamily are a key mediator of MSC chondrogenesis. While TGF-β mediated MSC chondrogenesis is well established in
Jennifer Patterson et al.
Biomaterials, 31(26), 6772-6781 (2010-06-25)
Non-healing fractures can result from trauma, disease, or age-related bone loss. While many treatments focus on restoring bone volume, few try to recapitulate bone organization. However, the native architecture of bone is optimized to provide its necessary mechanical properties. Hyaluronic
Jason A Burdick et al.
Advanced materials (Deerfield Beach, Fla.), 23(12), H41-H56 (2011-03-12)
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human body, is crucial for many cellular and tissue functions and has been in clinical use for over thirty years. When chemically modified, HA can be transformed into many
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