39953

Lauroyl-L-carnitine

≥95.0% (HPLC)

• Synonym(s): (-)-Lauroylcarnitine, dodecanoylcarnitine, (2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxododecyl)oxy]-1-propanaminium inner salt, L-Carnitine dodecanoyl ester, C12-Carnitine, Dodecanoyl-L-carnitine
• Empirical Formula (Hill Notation): C₁₉H₃₇NO₄
• CAS Number: 25518-54-1
• Molecular Weight: 343.50
• Beilstein/REAXYS Number: 4147610
• UNSPSC Code: 12352211
• PubChem Substance ID: 329755920
• NACRES: NA.26

Properties

• Quality Level: 100
• assay: ≥95.0% (HPLC)
• form: powder or crystals
• optical activity: [α]/D -20±2°, c = 1 in methanol
• packaging: pkg of 10 mg; pkg of 50 mg
• impurities: ≤10% water
• color: white to off-white
• functional group: ester
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O
• InChI: 1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1
• InChI key: FUJLYHJROOYKRA-QGZVFWFLSA-N

Description

General description

Lauroyl-L-carnitine, or Dodecanoylcarnitine, is an acylcarnitine compound with essential roles in energy metabolism. Synthesized in the liver from methionine, this metabolite of lysine is integral in various metabolic processes, making it a valuable asset in both biochemical and metabolomics research. Its concentration can serve as a diagnostic marker, particularly in cases of carnitine deficiency, and is of significance in assessing disease activity and diagnosing conditions like HIV and chronic hepatitis B infections. Additionally, Lauroyl-L-carnitine is associated with fatty acid oxidation disorders, including long-chain acyl CoA dehydrogenase deficiency and carnitine palmitoyltransferase I/II deficiency, further enhancing its relevance in metabolic research and diagnosis. This acylcarnitine compound has also been detected in cancer tissues, human serum, and tissue biopsies, expanding its applications and potential contributions to various areas of metabolomics research.

Application

Lauroyl-L-carnitine finds application in biochemical research and metabolomics research.

Biochem/physiol Actions

Lauroyl-L-carnitine is an acylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I deficiency, and carnitine palmitoyltransferase II deficiency.

Features and Benefits

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable