275R-3

Ki-67 (MRQ-64) Rabbit Monoclonal Antibody

clone MRQ-64, unconjugated, Cell Marque^™

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: MRQ-64, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (275R-34); vial of 0.1 mL concentrate Research Use Only (275R-34-RUO); vial of 0.5 mL concentrate (275R-35); vial of 1.0 mL concentrate (275R-36); vial of 1.0 mL concentrate Research Use Only (275R-36-RUO); vial of 1.0 mL pre-dilute Research Use Only (275R-37-RUO); vial of 1.0 mL pre-dilute ready-to-use (275R-37); vial of 25.0 mL pre-dilute ready-to-use (275R-30); vial of 25.0 mL pre-dilute ready-to-use Research Use Only (275R-30-RUO); vial of 7.0 mL pre-dilute ready-to-use (275R-38); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (275R-38-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotype: IgG
• control: Burkitt lymphoma, breast (ductl carcinoma in situ), tonsil
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... MKI67(4288)

Description

General description

Ki-67 (MRQ-64) is an antibody designed to target Ki-67 antigen-a nuclear protein encoded by the MKI67 gene whose presence correlates with G1, S, G2, and the mitotic phases of the cell cycle.¹ Though its specific role is largely postulated and still yet to be determined, Ki-67′s presence during cellular division makes it an excellent target for labeling rapidly growing malignancies.² Given that its presence correlates with cell proliferation, the immunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion′s growth fraction. It has been demonstrated that identifying this antigen by IHC is useful in characterizing lesions of the breast, lymphoid cells, astrocytes, and uterus.^3-9

Quality

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Linkage

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable