Y0001978

Biotin for system suitability

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Biotin, D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
• Empirical Formula (Hill Notation): C₁₀H₁₆N₂O₃S
• CAS Number: 58-85-5
• Molecular Weight: 244.31
• Beilstein/REAXYS Number: 86838
• EC Number: 200-399-3
• MDL number: MFCD00005541
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: EP
• API family: biotin
• form: solid
• manufacturer/tradename: EDQM
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 231-233 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
• InChI key: YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biotin is a hydro-soluble vitamin, which helps in the health of skin, nerve, digestive system and also serves as an important cofactor for mammalian carboxylases. It is found within the cells in free and bound pools and assists in releasing energy and metabolism of fats, protein and carbohydrates.

Application

Biotin may be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable