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Key Documents

SYNPLE-A011

Sigma-Aldrich

Reagent-cartridge Amide formation

Synple

Synonym(s):

Synple 2

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About This Item

MDL number:
MFCD32903606
UNSPSC Code:
12352401
NACRES:
NA.22

General description

Reagent-cartridge Amide formation is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the amide coupling of carboxylic acids and amines. The cartridge contains all necessary reagents for amide coupling and purification.

Scale: up to 0.5 mmol

Compatible substrates: carboxylic acids, primary and secondary alkyl amines

Cartridge contents:
  • Supported carbodiimide and Oxyma Pure (coupling reagents)
  • SCX2 (for purification)
  • Supported carbonate (acid scavenger)
Learn more about the Synple automated synthesis platform.


Features and Benefits of Synple Platform
  • Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
  • Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
  • Safety – all chemicals are contained in the system, minimizing the user’s exposure
  • Set-up reaction in less than 5 minutes
  • Small footprint
  • Plug & Play system – simple installation
  • Reaction temperatures from 25 °C – 80 °C
  • Cartridges available for many different reactions
  • Prefilled with all required reagentsRFID chip containing optimized reaction protocol
  • RFID chip containing optimized reaction protocol

Other Notes

References
An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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