PHR2858

Estradiol Benzoate

certified reference material, pharmaceutical secondary standard

• Synonym(s): β-Estradiol 3-benzoate, 1,3,5(10)-Estratriene-3,17β-diol 3-benzoate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate, 3-Benzoyloxy-17β-estrol
• Empirical Formula (Hill Notation): C₂₅H₂₈O₃
• CAS Number: 50-50-0
• Molecular Weight: 376.49
• Beilstein/REAXYS Number: 3107526
• MDL number: MFCD00003692
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to BP BP396; traceable to Ph. Eur. E1600000; traceable to USP 1251000
• description: Pharmaceutical Secondary Standard; Certified Reference Material
• API family: estradiol
• form: solid
• packaging: pkg of 500 mg
• mp: 191-198 °C (lit.)
• application(s): pharmaceutical small molecule
• storage temp.: 2-8°C
• SMILES string: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24
• InChI: 1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1
• InChI key: UYIFTLBWAOGQBI-BZDYCCQFSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H351,H360FD
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable