PHR1571

Methyl Oleate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Methyl oleate, Methyl cis-9-octadecenoate, Oleic acid methyl ester
• Linear Formula: CH₃(CH₂)₇CH=CH(CH₂)₇CO₂CH₃
• CAS Number: 112-62-9
• Molecular Weight: 296.49
• Beilstein/REAXYS Number: 1727037
• EC Number: 203-992-5
• MDL number: MFCD00009578
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1431556
• vapor pressure: 10 mmHg ( 205 °C)
• API family: methyl oleate
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• refractive index: n20/D 1.452 (lit.)
• bp: 218 °C/20 mmHg (lit.)
• density: 0.874 g/mL at 20 °C (lit.)
• application(s): pharmaceutical
• format: neat
• storage temp.: -10 to -25°C
• SMILES string: CCCCCCCC\C=C/CCCCCCCC(=O)OC
• InChI: 1S/C19H36O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21-2/h10-11H,3-9,12-18H2,1-2H3/b11-10-
• InChI key: QYDYPVFESGNLHU-KHPPLWFESA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methyl oleate can be obtained as one of the products of transesterification of triolein with methanol in the presence of potassium carbonate loaded onto alumina as catalyst.

Application

Methyl Oleate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas-chromatography (GC) coupled to flame-ionization detector (FID).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA4487 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113.0 °C - closed cup