95054

Azelaic acid

analytical standard

• Synonym(s): Nonanedioic acid
• Linear Formula: HO₂C(CH₂)₇CO₂H
• CAS Number: 123-99-9
• Molecular Weight: 188.22
• Beilstein/REAXYS Number: 1101094
• EC Number: 204-669-1
• MDL number: MFCD00004432
• UNSPSC Code: 85151701
• PubChem Substance ID: 329770414
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• vapor density: 6.5 (vs air)
• vapor pressure: <1 mmHg ( 20 °C)
• assay: ≥98.5% (GC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤0.5% water
• bp: 286 °C/100 mmHg (lit.)
• mp: 106-112 °C; 109-111 °C (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• format: neat
• SMILES string: OC(=O)CCCCCCCC(O)=O
• InChI: 1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
• InChI key: BDJRBEYXGGNYIS-UHFFFAOYSA-N

Description

General description

Azelaic acid (heptane-l,7-dicarboxylic acid), a dicarboxylic saturated acid, is an active component of some topical anti-acne preparations. It is reportedly identified in cosmetics and pharmaceuticals. Azelaic acid is found to suppress the growth of Propionibacterium spp. and reduce keratinization.

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Azelaic acid may be used as an analytical reference standard for the quantification of the analyte in the following:

• Tobacco using gas chromatography coupled to mass spectrometry (GC-MS).
• Topical preparations using reversed-phase liquid chromatographic (LC) with UV-Vis detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 410.0 °F - closed cup
• flash_point_c: 210 °C - closed cup