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Supelco

Ginkgolide B

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H24O10
CAS Number:
15291-77-7
Molecular Weight:
424.40
Beilstein/REAXYS Number:
4727611
MDL number:
MFCD05662347
UNSPSC Code:
85151701
PubChem Substance ID:
329770404
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤10.0% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]36[C@@H](O)C(=O)O[C@H]6O[C@@]4(C(=O)O5)[C@@]12O

InChI

1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11+,15+,17+,18+,19-,20-/m1/s1

InChI key

SQOJOAFXDQDRGF-MMQTXUMRSA-N

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General description

Ginkgolide B is a diterpenoid compound belonging to the group of ginkgolides, isolated from Ginkgo biloba leaves, exhibiting a wide spectrum of pharmacological properties and is used for the treatment of Alzheimer′s disease, cerebral insufficiency and memory loss.

Application

Ginkgolide B may be used as an analytical reference standard for the quantification of the analyte in phytopharmaceutical formulations and Ginkgo biloba L. extract using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: ginkgo

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7839
BCCG4211
BCCC0216
BCBW8672
BCBR9461V

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Leonid B Krivdin
Progress in nuclear magnetic resonance spectroscopy, 108, 17-73 (2018-12-13)
Structural applications of theoretical calculations of carbon-hydrogen spin-spin coupling constants are reviewed covering papers published mainly during the last 10-15 years with a special emphasis on the most notable studies of hybridization, substitution and stereoelectronic effects together with the investigation of
Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC
Chiu L-H, et al.
Analytical and Bioanalytical Chemistry, 379(3), 445-448 (2004)
Min Sun Choi et al.
Metabolites, 9(7) (2019-07-10)
Ginkgo leaf extract (GLE) is a popular herbal medicine and dietary supplement for the treatment of various diseases, including cardiovascular disease. GLE contains a variety of secondary plant metabolites, such as flavonoids and terpenoids, as active components. Some of these
Karyn M Maclennan et al.
Progress in neurobiology, 67(3), 235-257 (2002-08-10)
Ginkgo biloba extracts such as EGb-761 have been suggested to have a multitude of beneficial effects on CNS function, from enhancing cognitive function in dementia to facilitating recovery from acute forms of neural damage such as hypoxia/ischemia. Ginkgolide B, one
Xiao Chu et al.
Molecules (Basel, Switzerland), 16(9), 7634-7648 (2011-09-09)
Ginkgolide B is an anti-inflammatory extract of Ginkgo biloba and has been used therapeutically. It is a known inhibitor of platelet activating factor (PAF), which is important in the pathogenesis of asthma. Here, a non-infectious mouse model of asthma is
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