936669

DPPF ChemBeads

• Synonym(s): DPPF, 1,1′-Bis(diphenylphosphino)ferrocene ChemBeads, 1,1′-Ferrocenediyl-bis(diphenylphosphine) ChemBeads, 1,1′-Ferrocenediyl-bis(diphenylphosphine), dppf
• Empirical Formula (Hill Notation): C₃₄H₂₈FeP₂
• CAS Number: 12150-46-8
• Molecular Weight: 554.38
• MDL number: MFCD00001422
• UNSPSC Code: 12352100

Properties

• form: solid
• Quality Level: 100
• composition: loading, 4-6 wt. %
• mp: 181-182 °C (dec.) (lit.)
• SMILES string: [Fe].[CH]1[CH][CH][C]([CH]1)P(c2ccccc2)c3ccccc3.[CH]4[CH][CH][C]([CH]4)P(c5ccccc5)c6ccccc6
• InChI: 1S/2C17H14P.Fe/c2*1-3-9-15(10-4-1)18(17-13-7-8-14-17)16-11-5-2-6-12-16;/h2*1-14H;
• InChI key: HPXNTHKXCYMIJL-UHFFFAOYSA-N

Description

General description

The ChemBeads product of the 1,1′-Bis(diphenylphosphino)ferrocene (DPPF) ligand. DPPF is a bis-phosphine ligand bearing two diphenylphosphine moieties with a ferrocene backbone. Loaded on glass beads for use in high-throughput expermentation (HTE).

Application

• DPPF has been used as a ligand in:
• The ruthenium catalyzed N-alkylation of amines and sulfonamides using borrowing hydrogen methodology.[1] (19191700)
• The cooperative Cu/Pd catalyzed borylallenylation of trifluoromethyl-1,3-enynes to generate conjugated bisallenes.[2] (36321461)
• The cooperative Cu/Pd catlyzed borocarbonylation of ethylene.[3] (36226440)
• The gold catalyzed synthesis of 2-phosphoryl indolin-3-ones.[4] (35815915)
• The iron-catalyzed vinylzincation of terminal alkynes.[5] (34935372) ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.
• For general uses, product is also available in powdered form (177261)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable