402869

Chloramine T trihydrate

ACS reagent, 98%

• Synonym(s): N-Chloro-p-toluenesulfonamide sodium salt
• Linear Formula: CH₃C₆H₄SO₂NClNa · 3H₂O
• CAS Number: 7080-50-4
• Molecular Weight: 281.69
• Beilstein/REAXYS Number: 3924168
• EC Number: 204-854-7
• MDL number: MFCD00149066
• UNSPSC Code: 12352100
• PubChem Substance ID: 24865128
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• assay: 98%; 98.0-103.0% (ACS specification)
• form: powder
• reaction suitability: reagent type: oxidant
• impurities: <1.5% insolubles (alcohol)
• pH: 8.0-10.0 (25 °C, 5%)
• mp: 167-170 °C (lit.)
• solubility: H₂O: passes test
• suitability: passes test for determination of bromide
• SMILES string: O.O.O.Cc1ccc(cc1)S(=O)(=O)N([Na])Cl
• InChI: 1S/C7H7ClNO2S.Na.3H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;;;/h2-5H,1H3;;3*1H2/q-1;+1;;;
• InChI key: NZYOAGBNMCVQIV-UHFFFAOYSA-N

Description

General description

Chloramine T (CAT) trihydrate is a commonly used reagent for organic synthesis especially in heterocyclic chemistry. CAT is an active chlorine compound that shows antimicrobial activity.

Application

Chloramine T trihydrate may be used as an oxidizing agent in the synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives and novel isoxazolines.
It may also be used in the synthesis of the following compounds:

• Nitrile imines by the oxidative dehydrogenation of N-(nitrobenzyl)-imidazole aldehyde hydrazine.
• Mono-N-tosylated-1,2-diamines.
• 3,5-Disubstituted isoxazoles.
• Fused 3,6-disubstituted triazolothiadiazoles by the oxidative cyclization of N-heteroaryl-substituted hydrazones.

Nitrene source for aziridinations and aminohydroxylations.

Packaging

Capable of oxidative cyclization to produce various heterocycles.

Safety Information

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314,H334
• pcodes: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
• supp_hazards: EUH031
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: 377.6 °F - closed cup
• flash_point_c: 192 °C - closed cup