32249-M

Toluene

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.7% (GC)

• Linear Formula: C₆H₅CH₃
• CAS Number: 108-88-3
• Molecular Weight: 92.14
• Beilstein/REAXYS Number: 635760
• EC Number: 203-625-9
• MDL number: MFCD00008512
• UNSPSC Code: 12352005
• eCl@ss: 39011102
• PubChem Substance ID: 329754114
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• Quality Level: 200
• agency: USP/NF; reag. ISO; reag. Ph. Eur.
• vapor density: 3.2 (vs air)
• vapor pressure: 22 mmHg ( 20 °C); 26 mmHg ( 25 °C)
• assay: ≥99.7% (GC)
• form: liquid
• autoignition temp.: 997 °F
• expl. lim.: 7 %
• impurities: ≤0.0001% thiophene; ≤0.001% free acid (as HCl); ≤0.001% free alkali (as NaOH); ≤0.001% non-volatile matter; ≤0.003% S-compounds (as S); ≤0.02% water (Karl Fischer)
• color: APHA: ≤10
• refractive index: n/D 1.496 (lit.); n20/D 1.496-1.498
• bp: 110-111 °C (lit.)
• mp: -93 °C (lit.)
• density: 0.865 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 ppm; Ba: ≤0.1 ppm; Bi: ≤0.1 ppm; Ca: ≤0.5 ppm; Cd: ≤0.05 ppm; Co: ≤0.02 ppm; Cr: ≤0.02 ppm; Cu: ≤0.02 ppm; Fe: ≤0.1 ppm; K: ≤0.5 ppm; Li: ≤0.1 ppm; Mg: ≤0.1 ppm; Mn: ≤0.02 ppm; Mo: ≤0.1 ppm; Na: ≤0.5 ppm; Ni: ≤0.02 ppm; Pb: ≤0.1 ppm; Sr: ≤0.1 ppm; Zn: ≤0.1 ppm
• SMILES string: Cc1ccccc1
• application(s): microbiology
• InChI: 1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
• InChI key: YXFVVABEGXRONW-UHFFFAOYSA-N

Description

General description

Toluene, a benzene analog, is widely employed as an organic solvent. It has been reported to be a biotoxic solvent (toxic to many microorganisms at 0.1% v/v concentrations). Its anaerobic biodegradation to CO₂, by the denitrifying bacterium Thauera arornatica has been reported. It forms syndiotactic polystyrene-toluene molecular compound. Crystal structure of this molecular compound has been investigated by X-ray diffraction studies.

Application

Toluene may be used for decontamination of microbial cultures and lyse bacterial cells in bacterial enzyme assays. It may be used as a solvent for the preparation of 4-arm polylactide-based (PLA) star oligomer. It was used for the activation of glass slides, for in vitro test system for allergy diagnosis.

Other Notes

Pertains only in Germany: unversteuert

Safety Information

• pictograms: GHS02,GHS07,GHS08
• signalword: Danger
• hcodes: H225 - H304 - H315 - H336 - H361d - H373 - H412
• pcodes: P202 - P210 - P273 - P301 + P310 - P303 + P361 + P353 - P331
• Hazard Classifications: Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 39.2 °F - closed cup
• flash_point_c: 4 °C - closed cup