32002

Sodium 5,5-diethylbarbiturate

purum, ≥99.0% (NT)

• Synonym(s): 5,5-Diethylbarbituric acid sodium salt, Barbitone, Sodium barbital, Veronal sodium salt
• Empirical Formula (Hill Notation): C₈H₁₁N₂NaO₃
• CAS Number: 144-02-5
• Molecular Weight: 206.17
• Beilstein/REAXYS Number: 3921202
• EC Number: 205-613-9
• MDL number: MFCD00036203
• UNSPSC Code: 12161703
• PubChem Substance ID: 329753946
• NACRES: NA.77

Properties

• grade: purum
• Quality Level: 200
• assay: ≥99.0% (NT)
• form: powder or crystals
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• storage condition: (Tightly closed. Dry.)
• technique(s): GC/MS: suitable; HPLC: suitable; activity assay: suitable
• color: colorless
• pH: 9.0-10.5
• mp: >287.1 °C (> 548.8 °F)
• solubility: water: soluble 103.1 g/L at 20 °C (68 °F)
• density: 1.418 g/cm³ at 20 °C ( 68 °F)
• suitability: suitable for microbiology; suitable for molecular biology
• application(s): cell analysis
• SMILES string: [Na+].CCC1(CC)C(=O)NC([O-])=NC1=O
• InChI: 1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1
• InChI key: RGHFKWPGWBFQLN-UHFFFAOYSA-M

Description

General description

Sodium 5,5-diethyl barbiturate, also known as Barbital sodium, is a long-acting barbiturate that can significantly depress various metabolic processes at high doses. This weak acid has widespread applications in scientific fields, particularly as a buffering solution in biochemical and biological experiments due to its buffering capabilities. It is particularly well-suited for scenarios requiring lower buffer capacity without compromising pH stability. This buffering effect is achieved through the equilibrium between the acid and its corresponding anion, effectively stabilizing the pH within the desired range. Additionally, Sodium 5,5-diethyl barbiturate has potential applications in histology, and biochemical research, including uses in enzyme assays, cell structure staining, and electrophoresis.

Application

Sodium 5,5-diethyl barbiturate has been used as a component of Michaeli′s buffer, a commonly used buffer solution that helps maintain ideal conditions for histological and histopathological analyses. It is also utilized as a biological buffer in immunoelectrophoresis, hemolytic assays and fixative solutions.

Biochem/physiol Actions

Sedative/hypnotic

Features and Benefits

• Suitable for electrophoresis and enzymatic assays
• High purity product for research applications
• Component of Michaeli′s buffer

Warning

Substance of abuse. Regulatory approval may be required for purchase. Comply with applicable laws. Exercise responsible use.

Other Notes

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This product is intended for research purposes only, and it is not meant for human consumption.

Sales restrictions may apply

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361d,H371
• pcodes: P202 - P260 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P311
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3
• target_organs: Nervous system, Respiratory system
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves