304050

Triethyl orthoformate

anhydrous, 98%

• Synonym(s): Diethoxymethoxyethane, 1,1,1-Triethoxymethane
• Linear Formula: CH(OC₂H₅)₃
• CAS Number: 122-51-0
• Molecular Weight: 148.20
• Beilstein/REAXYS Number: 605384
• EC Number: 204-550-4
• MDL number: MFCD00009230
• UNSPSC Code: 12352001
• PubChem Substance ID: 24858320
• NACRES: NA.21

Properties

• grade: anhydrous
• Quality Level: 100
• vapor density: 5.11 (vs air)
• vapor pressure: 2.9 mmHg ( 20 °C)
• assay: 98%
• form: liquid
• impurities: <0.003% water; <0.005% water (100 mL pkg)
• evapn. residue: <0.0005%
• refractive index: n20/D 1.391 (lit.)
• bp: 146 °C (lit.)
• mp: −76 °C (lit.)
• density: 0.891 g/mL at 25 °C (lit.)
• SMILES string: CCOC(OCC)OCC
• InChI: 1S/C7H16O3/c1-4-8-7(9-5-2)10-6-3/h7H,4-6H2,1-3H3
• InChI key: GKASDNZWUGIAMG-UHFFFAOYSA-N

Description

Application

Triethyl orthoformate may be used to synthesize:

• Formyl ferrocene by reacting with ferrocene in the presence of aluminium chloride.
• 5-Nitropyridines via cyclocondensation with nitroacetone and different enamines.
• 3-Aryl-4(3H)-quinazolinones by reacting with anthranilic acid via heterocyclization catalyzed by concentrated sulfuric acid.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 95.0 °F - closed cup
• flash_point_c: 35 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter