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04068

Sigma-Aldrich

Fmoc-11-Aun-OH

≥98.0% (HPLC)

Synonym(s):

11-(Fmoc-amino)undecanoic acid

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About This Item

Empirical Formula (Hill Notation):
C26H33NO4
CAS Number:
Molecular Weight:
423.54
Beilstein/REAXYS Number:
4887890
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

color

white

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)CCCCCCCCCCNC(=O)OCC1c2ccccc2-c3ccccc13

InChI

1S/C26H33NO4/c28-25(29)17-7-5-3-1-2-4-6-12-18-27-26(30)31-19-24-22-15-10-8-13-20(22)21-14-9-11-16-23(21)24/h8-11,13-16,24H,1-7,12,17-19H2,(H,27,30)(H,28,29)

InChI key

IMEVDILDSCXKJW-UHFFFAOYSA-N

Other Notes

Alkyl spacer employed in peptide synthesis.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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D. Boumrah et al.
Tetrahedron, 53, 6977-6977 (1997)
C Galoppini et al.
Journal of medicinal chemistry, 42(3), 409-414 (1999-02-13)
Four previously reported kinin receptor peptide antagonists, including the B1 receptor-selective peptides desArg10-HOE 140 (H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-OH) and B-9858 (H-Lys-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-Igl-Oic-OH), have been modified by replacement of the central tetrapeptide Pro-Hyp-Gly-Xaa with linear alkyl spacers of variable length. The analogue of desArg10-HOE 140

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