MABN445

Anti-Synaptotagmin-like protein 1 (SYTL1 Antibody), clone 2F2.2

clone 2F2.2, 1 mg/mL, from mouse

• Synonym(s): Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 2F2.2, monoclonal
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_001180237
• UniProt accession no.: Q8IYJ3
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SYTL1(84958)

Description

General description

Synaptotagmin-like protein 1 (SYTL1), also known as Exophilin-7, Protein JFC1, and encoded by the gene SYTL1/SLP1, is an important protein in exocytosis. Synaptotagmin-like protein 1 plays a role in vesicle trafficking and is important in exocytosis in lymphocytes and other cells including neurons, platelets and most cells that secrete materials via exocytosis. Synaptotagmin-like protein 1 is highly expressed in bone marrow and lymphoid tissues as well as cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea.

Immunogen

GST-tagged recombinant protein corresponding to human Synaptotagmin-like protein 1 (SYTL1).

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Synaptotagmin-like protein 1 (SYTL1) in human cerebral cortex and human tonsil tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This Anti-Synaptotagmin-like protein 1 (SYTL1 Antibody), clone 2F2.2 is validated for use in western blotting & IHC for the detection of Synaptotagmin-like protein 1 (SYTL1).

Quality

Evaluated by Western Blotting in human lymph node tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Synaptotagmin-like protein 1 (SYTL1) in 10 µg of human lymph node tissue lysate.

Target description

~62 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable