MABC1593

Anti-CRBN Antibody, clone 4D6

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• antibody form: purified antibody
• clone: 4D6 (-3H10-D6); monoclonal
• purified by: using protein G
• species reactivity: human, mouse, human
• concentration: (Please refer to lot specific datasheet.)
• technique(s): immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG1κ
• UniProt accession no.: Q96SW2

Description

General description

His-tagged recombinant protein fragment corresponding to the N-terminal region of human Cereblon.

Specificity

Clone 4D6 (-3H10-D6) is a mouse monoclonal antibody that detects human Cereblon. It targets an epitope within the N-terminal domain.

Application

Western Blotting Analysis: 20 ug from a representative lot detected CRBN in MOLT4 wild type cell lysates (Courtesy of Stefan Schuchner, Ph.D. and Egon Ogris, M.D., Medical University of Vienna, Austria).

Immunoprecipitation Analysis: A representative lot immunoprecipitated CRBN in MOLT4 wild type cell lysates (Courtesy of Stefan Schuchner, Ph.D. and Egon Ogris, M.D., Medical University of Vienna Austria).

Quality

Evaluated by Western Blotting in MOLT-4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Cereblon.(CRBN) in MOLT-4 cell lysate.

Physical properties

~50 kDa observed; 50.55 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Physical form

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.