MAB4388

Mouse Anti-Stella Antibody

clone 3H5.2, Chemicon^®, from mouse

• Synonym(s): Anti-Anti-Pgc7, Anti-Anti-STELLA
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 3H5.2, monoclonal
• species reactivity: mouse, human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable; immunocytochemistry: suitable
• input: sample type: human embryonic stem cell(s); sample type induced pluripotent stem cell(s); sample type: mouse embryonic stem cell(s)
• isotype: IgG1
• NCBI accession no.: NM_199286.2
• UniProt accession no.: Q6W0C5
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Dppa3(73708)

Description

General description

Stella is specifically expressed by oocytes, pluripotent cells and primordial germ cells at the time of their emergence in gastrulating embryos, and is an important maternal factor in the cleavage stages of mouse embryos (Bortvin, 2004). The requirement for stella in germ cell specification remains controversial, however, most embryos from stella deficient mice failed to develop normally and rarely reach the blastocyst stage (Bortvin, 2004; Payer, 2003). The stella gene encodes a protein with an SAP-like domain and splicing factor motif-like structure, suggesting possible roles in chromosomal organization and RNA processing (Payer, 2003).

Specificity

Reacts with stella from human and mouse.

Application

Mouse Anti-Stella Antibody detects level of Stella & has been published & validated for use in ELISA & IC.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

Physical form

Format: Purified

Purified Immunoglobulin presented as a liquid in PBS with 0.1% sodium azide.

Storage and Stability

Maintain refrigerated at 2-8C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable