HNDG2MAG-36K

MILLIPLEX^® Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.

• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Properties

• Quality Level: 200
• species reactivity: human
• manufacturer/tradename: Milliplex^®
• assay range: accuracy: 84%; (SAP); accuracy: 88%; (Complement C4); accuracy: 92%; (α-1-Antitrypsin); accuracy: 92%; (PEDF); accuracy: 95%; (MIP-4); standard curve range: 0.05-200 ng/mL; (PEDF); standard curve range: 0.10-50 ng/mL; (CRP); standard curve range: 0.12-500 ng/mL; (SAP); standard curve range: 0.24-1,000 ng/mL; (α-1-Antitrypsin); standard curve range: 0.24-1,000 ng/mL; (Complement C4); standard curve range: 4.88-20,000 ng/mL; (MIP-4)
• technique(s): multiplexing: suitable
• detection method: fluorometric (Luminex xMAP)
• shipped in: wet ice

Description

General description

The MILLIPLEX^® Human Neurodegenerative Bead Panel 2 (HNDG2MAG-36K) is to be used for the simultaneous quantification of the following analytes in any combination: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.

Neurodegenerative disease is a condition characterized by the deterioration of neurons or their myelin sheath over time in the brain and/or spinal cord. These neurons are responsible for such everyday activities as processing sensory information, making decisions, and controlling movement. Because these cells are not easily regenerated, excessive cumulative damage can lead to age-related diseases such as Alzheimer′s and Parkinson′s disease, as well as other conditions such as amyotrophic lateral sclerosis (ALS) and epilepsy. These disorders are devastating and expensive, both on a personal and global level, and as population demographics continue to change, a therapeutic solution is critical. Consequently, research is underway to identify biomarkers that will help scientists not only understand the pathogenesis of neurodegenerative disease, but also identify people with these disorders before the onset of symptoms and potentially provide new therapeutic tools.

Panel Type: Neuroscience

Specificity

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

• Analytes: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP
• Recommended Sample type: serum, plasma and CSF
• Recommended Sample dilution: 1:2,000 diluted serum/plasma or 1:20 diluted CSF
• Assay Run Time: Overnight
• Research Category: Neuroscience
• Research Subcategory: Alzheimer′s Disease Nervous System

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Packaging

Everything you need in a single kit.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.

Other Notes

Sensitivity: See kit protocol for individual sensitvities

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• pictograms: GHS08,GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302 + H312 + H332,H317,H318,H373,H411
• pcodes: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• target_organs: Respiratory Tract
• Storage Class: 10 - Combustible liquids