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Key Documents

AB907

Sigma-Aldrich

Anti-Desmin Antibody

serum, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, bovine, chicken, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... DES(1674)

Specificity

Desmin. Reacts specifically with desmin in cultured cells or tissue preparations originating from chicken, human, bovine and mouse tissue. AB907 specifically stains the wide desmin band in immunoblot at a molecular weight of 50-55 kD.

Immunogen

Purified desmin from chicken gizzard, isolated by modified procedure of Geisler, et al [J. Biol Chem. (1980). 111:425-433].

Application

Anti-Desmin Antibody is an antibody against Desmin for use in WB, IH(P).
Indirect immunofluorescence of formalin fixed paraffin-embedded sections of human intestine sections: 1:10-1:20.

Immunoblotting

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Cytoskeleton

Linkage

Replaces: 04-585

Physical form

Rabbit antiserum. Liquid containing 0.1% sodium azide as a preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue.
Raymond, F; Metairon, S; Kussmann, M; Colomer, J; Nascimento, A; Mormeneo et al.
BMC Genomics null
E Lazarides et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(12), 4344-4348 (1976-12-01)
We report the immunological characterization of the subunit of the intermediate sized (100 A) filaments from muscle cells. The protein as isolated from smooth muscle (chicken gizzard) has an apparent molecular weight of 50,000. It is insoluble in buffers that
Richard Sharp et al.
Nature medicine, 8(11), 1276-1280 (2002-10-09)
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children, yet molecular events associated with the genesis and progression of this potentially fatal disease are largely unknown. For the molecules and pathways that have been implicated, genetic validation has been
Copurification of actin and desmin from chicken smooth muscle and their copolymerization in vitro to intermediate filaments.
Hubbard, B D and Lazarides, E
The Journal of cell biology, 80, 166-182 (1979)
Immunocytochemical localization of desmin at human neuromuscular junctions.
Askanas, V, et al.
Neurology, 40, 949-953 (1990)

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