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AB3421

Sigma-Aldrich

Anti-Complement C3 Antibody

Chemicon®, from chicken

Synonym(s):

Anti-AHUS5, Anti-ARMD9, Anti-ASP, Anti-C3a, Anti-C3b, Anti-CPAMD1, Anti-HEL-S-62p

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

chicken

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable

NCBI accession no.

NM_000064.2

UniProt accession no.

P01024

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... C3(718)

Specificity

Complement C3

Immunogen

Human C3, full length plasma protein.

Application

Detect Complement C3 using this Anti-Complement C3 Antibody validated for use in ELISA.
ELISA, direct: 0.1 μg/mL

It is expected that the antibody will also work for Western blot, immunohistochemistry and immunocytochemistry. Specific reactivity has not been confirmed.

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

Physical form

Chicken IgY fraction, in 0.15 M NaCl, 0.02 M NaH2PO4, 0.1% NaN3, pH 7.2.

Storage and Stability

Maintain at 2-8*C in undiluted aliquots up to 6 months after date of receipt.
Avoid freezing temperatures.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mercedes Domínguez et al.
The Journal of experimental medicine, 195(4), 451-459 (2002-02-21)
In normal human serum (NHS), axenic promastigotes of Crithidia, Phytomonas, and Leishmania trigger complement activation, and from 1.2 to 1.8 x 10(5) C3 molecules are deposited per promastigote within 2.5 min. In Leishmania, promastigote C3 binding capacity remains constant during
Pizga Kumwenda et al.
Cell reports, 38(1), 110183-110183 (2022-01-06)
Candida albicans is a commensal of the urogenital tract and the predominant cause of vulvovaginal candidiasis (VVC). Factors that increase circulatory estrogen levels such as pregnancy, the use of oral contraceptives, and hormone replacement therapy predispose women to VVC, but

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