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Key Documents

AB10200

Sigma-Aldrich

Anti-Perilipin A Antibody

Chemicon®, from rabbit

Synonym(s):

Anti-FPLD4, Anti-PERI, Anti-PLIN

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

bovine, mouse

packaging

antibody small pack of 25 μg

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_002666.3

UniProt accession no.

O60240

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Plin1(103968)

General description

Perilipin A is the predominant isoform of perilipins a family of proteins which are the most abundant proteins at the surfaces of lipid droplets in adipocytes and are also found in steroidogenic cells.

Immunogen

Bovine Perilipin A

Application

Suggested dilutions:
Western Blot: 0.1-0.2 μg/mL
Detect Perilipin A using this Anti-Perilipin A Antibody validated for use in WB.
Research Category
Metabolism
Research Sub Category
Lipid Metabolism & Weight Regulation

Quality

Routinely evaluated by immunoblot.

Target description

64kDa

Physical form

Format: Purified
Purified immunoglobulin presented as a liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing protease free bovine serum albumin.

Storage and Stability

Maintain frozen at -20C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze-thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Coordination of lipid droplet-associated proteins during the transition period of Holstein dairy cows.
Koltes DA, Spurlock DM
Journal of Dairy Science null
Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages.
Larigauderie, Guilhem, et al.
Atherosclerosis, 189, 142-148 (2006)
Hideaki Miyoshi et al.
The Journal of biological chemistry, 282(2), 996-1002 (2006-11-23)
Phosphorylation of the lipid droplet-associated protein perilipin A (Peri A) mediates the actions of cyclic AMP-dependent protein kinase A (PKA) to stimulate triglyceride hydrolysis (lipolysis) in adipocytes. Studies addressing how Peri A PKA sites regulate adipocyte lipolysis have relied on
Expression of perilipin A on the surface of lipid droplets increases along with the differentiation of hamster sebocytes in vivo and in vitro
Akimoto, Noriko, et al
The Journal of Investigative Dermatology, 124, 1127-1133 (2005)
mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes.
Ghada A Soliman,Hugo A Acosta-Jaquez,Diane C Fingar
Lipids null
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