580559

Paclitaxel, 6α-Hydroxy-

A metabolite of the anticancer agent Paclitaxel.

• Synonym(s): Paclitaxel, 6α-Hydroxy-, 6-Hydroxytaxol
• Empirical Formula (Hill Notation): C₄₇H₅₁NO₁₅
• CAS Number: 153212-75-0
• Molecular Weight: 869.91
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: colorless
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C47H51NO15/c1-24-30(61-43(57)33(51)32(27-16-10-7-11-17-27)48-41(55)28-18-12-8-13-19-28)22-47(58)40(62-42(56)29-20-14-9-15-21-29)36-45(6,38(54)35(60-25(2)49)31(24)44(47,4)5)37(53)34(52)39-46(36,23-59-39)63-26(3)50/h7-21,30,32-37,39-40,51-53,58H,22-23H2,1-6H3,(H,48,55)/t30-,32-,33+,34-,35+,36-,37-,39+,40-,45-,46+,47+/m0/s1
• InChI key: NDCWHEDPSFRTDA-FJMWQILYSA-N

Description

General description

A metabolite of the anticancer agent Paclitaxel (Cat. No. 580555).

A metabolite of the anticancer agent Paclitaxel (Cat. No. 580555). Note: 20 nmol = 17.4 µg.

Note: 20 nmol = 17.4 µg.

Biochem/physiol Actions

Cell permeable: no

Primary Target
A metabolite of the anticancer agent Paclitaxel

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Other Notes

Baldwin, S.J., et al. 1999. Br. J. Clin. Pharmacol.48, 424.
Fischer, V., et al. 1999. Drug Metab. Dispos.27, 410.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 953.8 - 1041.3 °F
• flash_point_c: 512.1 - 560.7 °C