475828

β₂-Microglobulin, Human, Recombinant, E. coli

• Synonym(s): rhβ₂M
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• form: lyophilized
• Quality Level: 100
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• solubility: aqueous buffer: soluble
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Recombinant, human β₂-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Recombinant, human β₂-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

single band by SDS-PAGE

Other Notes

Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613.
Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable