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Supelco

LiChrospher® 100 CN (5 µm) HPLC Columns

L x I.D. 125 mm x 4 mm LiChroCART™ HPLC cartridge, manuCART™ holder required for use

Synonym(s):

TM=["LiChrospher"] Cyano TM=["LICHROCART"] cartridge for HPLC

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About This Item

UNSPSC Code:
41115709
NACRES:
SB.52

product name

LiChrospher® 100 CN (5 µm) LiChroCART™ 125-4, suitable for HPLC

material

stainless steel column

Quality Level

100

agency

suitable for USP L10

product line

LiChrospher®

feature

endcapped: no

extent of labeling

6.6% Carbon loading

parameter

250 bar pressure
60 °C max. temp.

technique(s)

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

column L × I.D.

12.5 cm × 4 mm

surface area

350 m2/g

matrix

fully porous particle

matrix active group

Cyano (CN) bonding phase

particle size

5 μm

pore size

100 Å pore size

operating pH range

2-7.5

separation technique

hydrophilic interaction (HILIC)
normal phase
reversed phase

storage temp.

no temp limit

General description

HPLC cartridge
LiChrospher® CN has polar and hydrophobic properties, thus can be used as less polar alternative to LiChrospher Si 60 in normal phase applications or as less hydrophobic alternative to LiChrospher RP-8 in reversed phase applications. This sorbent is packed into a LiChroCART 125-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).

Application


  • Development and validation of an HPLC method to determine the stability of fentanyl citrate and bupivacaine hydrochloride mixtures in infusion solutions.: This study developed and validated an HPLC method using LiChrospher® 100 CN for analyzing the stability of fentanyl citrate and bupivacaine hydrochloride in infusion solutions. The method showed high precision and accuracy, making it suitable for routine stability testing in hospital pharmacies (Piekarski et al., 2012).

Analysis Note

Pressure: ≤ 30 bar
Theoretical Plates (N/m) (2-Nitrotoluene): ≥ 40000
Symmetry (2-Nitrotoluene): 0.8 - 1.4
Capacity factor (2-Nitrotoluene): 0.5 - 1.5

Legal Information

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

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