1.41517

PARTECK^® COAT (Polyvinyl alcohol)

EMPROVE^® ESSENTIAL, Ph. Eur., ChP, JPE, USP

• Synonym(s): Parteck^® Polyvinyl alcohol, PVA, PVOH
• Linear Formula: (C₂H₄O)_n
• CAS Number: 9002-89-5
• MDL number: MFCD00081922
• UNSPSC Code: 13111042

Properties

• agency: ChP; JPE; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: fine powder
• particle size: 180-260 μm (d50)
• mp: 160-240 °C
• application(s): pharmaceutical; solid formulation
• shipped in: ambient
• storage temp.: 15-25°C
• InChI: 1S/C2H4O/c1-2-3/h2-3H,1H2
• InChI key: IMROMDMJAWUWLK-UHFFFAOYSA-N

Description

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck^® COAT excipient is a particle-engineered polyvinyl alcohol (PVA) with a unique structure specifically designed for immediate release film coating application. Due to its optimized particle size, it helps to reduce dissolving times when preparing the coating solution, thus increasing process efficiency. Parteck^® COAT excipient can be combined with a variety of supporting excipients such as plasticizers, anti-tacking agents and pigments – all available in our portfolio – to give you full flexibility in designing just the right coating for your need, and in the right timeframe. It is also very well-suited for coating ODT formulations using the Parteck^® ODT orally disintegrating excipient system.

Features and Benefits

• Excellent surface finishing - improve the appearance of your formulation
• Rapid preparation of coating liquids even at room temperature
• Low viscosity of coating liquids at high polymer concentration – enables reduced process times and enhanced efficiency
• Stable moisture and oxygen barrier - effective protection of moisture-sensitive APIs

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1