1.41439

Parteck^® SRP 80 (Polyvinyl alcohol)

EMPROVE^® ESSENTIAL, Ph. Eur., ChP, USP, JPE

• Synonym(s): Parteck^® Polyvinyl alcohol, PVA, PVOH
• Linear Formula: (C₂H₄O)_n
• CAS Number: 9002-89-5
• MDL number: MFCD00081922
• UNSPSC Code: 13111042

Properties

• agency: ChP; JPE; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: fine powder
• particle size: 60-100 μm (d50)
• mp: 160-240 °C
• application(s): controlled release; pharmaceutical; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C2H4O/c1-2-3/h2-3H,1H2
• InChI key: IMROMDMJAWUWLK-UHFFFAOYSA-N

Description

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck^® SRP 80, a functional, fully synthetic excipient based on polyvinyl alcohol (PVA), provides consistent, sustained drug delivery over long release periods. Due to its optimized particle properties, Parteck^® SRP 80 excipient has a high compressibility and high dilution potential as well as reliable in-vitro drug dissolution.

Features and Benefits

• Reliable sustained release profiles of active pharmaceutical ingredients over several hours
• Suitable for direct compression processes with conventional equipment
• Resistant to pH- and alcohol-induced dose dumping
• Superior batch-to-batch consistency and robust performance due to fully synthetic material

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1