1.20089

Eshmuno^® A Resin

Eshmuno® A, affinity

• Synonym(s): Eshmuno^® A
• UNSPSC Code: 23151817

Properties

• ligand: protein A
• Quality Level: 400
• form: resin
• specific analyte(s): MAbs
• manufacturer/tradename: Eshmuno^®
• parameter: >500 cm/hr flow rate; 8 bar max. pressure
• matrix active group: polymer, polyvinyl ether
• mean particle size: 50 μm
• capacity: 40-55 mg/mL binding capacity
• transition temp: flash point 35 °C (calculated)
• separation technique: affinity
• storage temp.: 2-8°C

Description

General description

Protein A affinity resin based on polyvinyl ether base matrix

Features and Benefits

Eshmuno^® A chromatography resin provides users with:

• An Intensified processes resulting in High Binding Capacity, Superior Flow Capability, and Excellent HCP reduction.
• Products purity with a more consistent viral clearance, increased aggregate removal, reduced fab finding and low leached Protein A
• High dynamic binding capacity at high flow rate
• Aggregate removal, Alkaline Stability and Acid cleaning compatibility

Packaging

• 1.20089.0100: Eshmuno^® A Resin 100 ml
• 1.20089.9010: Eshmuno^® A Resin 10 L
• 1.20089.0010: Eshmuno^® A Resin 10 ml
• 1.20089.0500: Eshmuno^® A Resin 500 ml
• 1.20089.5000: Eshmuno^® A Resin 5 L

Plastic bottle

Analysis Note

Appearance: Milky turbid suspension, free from coarse mechanical impurities
Microscopic evaluation: Spherical particles, no agglomerates, no fines
Particle size (30 – 70 µm): ≥ 80 %
Endotoxins: ≤ 1.00 EU/ml
TAMC (Total aerobic microbial count): ≤ 100 CFU/ml
TYMC (Total yeast and mould count): ≤ 100 CFU/ml
Capacity (IgG): ≥ 55 mg/ml
Leakage (Protein A): ≤ 100 ppm

Legal Information

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 95.0 °F
• flash_point_c: 35 °C