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Buffer concentrate

(borate/hydrochloric acid), traceable to SRM of NIST and PTB for 500 ml buffer solution, pH 8.00 ± 0.02 (20°C) Titrisol®

Synonym(s):

Buffer concentrate for 500 ml buffer solution, pH 8.00 ± 0.02 (20°C)

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About This Item

UNSPSC Code:
12161705
NACRES:
NA.25

grade

analytical standard

Quality Level

100

agency

according to DIN 19266

product line

Titrisol®

pH

8.00 (20 °C in H2O)

density

1.00 g/cm3 at 20 °C

application(s)

environmental
food and beverages
general analytical
industrial qc
pharmaceutical

format

mixture

storage temp.

15-25°C

General description

The Titrisol® reference buffer concentrate [borate/hydrochloric acid; pH=8.00±0.02 (20 °C)] is analyzed in the ISO/IEC 17025 accredited calibration laboratory with a combined glass electrode and 5-point calibration according to DIN 19268 against a certified primary standard reference material following DIN 19266.

The Titrisol® concentrated buffer material combines ease of use and maximum precision for the routine calibration and monitoring of pH instruments. To prepare the ready-to-use pH buffer solution, simply dilute the Titrisol® buffer concentrate.

Application


  • Optimizing oral bioavailability in pharmaceuticals: Buffer concentrate is integral to the formulation of proniosomal drug delivery systems, as seen in the development of Irbesartan formulations where it enhances solubility and stability, facilitating improved bioavailability and therapeutic efficacy (Mujtaba et al., 2024).

  • Environmental remediation: In environmental science, buffer concentrate is used to adjust the pH of solutions, ensuring optimal conditions for the mediation of electron transfers in contaminant remediation processes, particularly in treatments involving heavy metals like chromium (Li and Zhang, 2024).

  • Biomedical research: Buffer concentrates are crucial for maintaining pH stability in biomedical experiments, such as studies on hemoglobin mass in response to apnea, which require precise control over biochemical conditions (Keeler et al., 2024).

  • Chemical analysis: In analytical chemistry, buffer concentrates are used to stabilize the environment during the voltammetric determination of dyes, ensuring accuracy and repeatability in the detection of chemical substances (Moulya et al., 2024).

Features and Benefits

  • Traceable to primary standard reference materials from NIST and PTB
  • Analytical standard Grade
  • Uncertainty data and traceability are documented in a comprehensive and batch-specific Certificate of Analysis.

Analysis Note

pH-value (20 °C): 8.00 ± 0.02
Measured after dilution to 500 ml with a combination glass electrode after multiple point calibration (according to DIN 19268) with reference materials for the preparation of standard buffer solutions according to DIN 19266.

Legal Information

Titrisol is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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