104648
Cellvento® ModiFeed Gal- COMP
Chemically defined cell culture feed - EMPROVE® CCM
Pharma Manufacturing
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About This Item
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Quality Level
description
shipped with cooling packs
form
dry powder
technique(s)
cell culture | mammalian: suitable
storage temp.
2-8°C
Related Categories
General description
Cellvento® ModiFeed Gal- COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously reducing galactosylation on the protein of interest. It is recommened in combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO Fed-batch medium or other production media.
Application
Glycosylation is known to have effects on the biological activity, solubility, serum half-life, and saftey of therapeutic proteins. Control of protein glycosylation processes, such as galactosylation, while maximizing productivity is key for successful mAb process development and production. Cellvento® ModiFeed Gal- COMP was developed to increase G0(F), while maintaining or improving titer in CHO fed-batch processes.
Features and Benefits
- Reduced complexity in fed-batch process
- Complete feed maximizing galactosylation
- Highly concentrated to reduce required feed volume
- Compacted format for conventient handling
- Higher liquid feed stability at room temperature
Quantity
Formulated to contain 143.6 grams of powder per liter of feed.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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