1.00662

Sorbic acid

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, NF, FCC, E 200

• Synonym(s): Sorbic acid, 2,4-Hexadienic acid
• Empirical Formula (Hill Notation): C₆H₈O₂
• CAS Number: 110-44-1
• Molecular Weight: 112.13
• MDL number: MFCD00002703
• UNSPSC Code: 12352106
• E Number: E200
• EC Index Number: 203-768-7

Properties

• agency: BP; ChP; NF; Ph. Eur.
• Quality Level: 500
• reg. compliance: FCC
• vapor pressure: 0.00018 hPa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 99.0-101.0% substance (anhydrous) basis (acidimetric)
• form: solid
• autoignition temp.: >130 °C
• technique(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 3.3 (20 °C, 1.6 g/L in H₂O)
• bp: 160-260 °C/1013 hPa (decomposition)
• mp: 120-150 °C
• solubility: 1.6 g/L
• density: 1.2 g/cm³ at 20 °C
• cation traces: As: ≤0.0003%; Cd: ≤0.001%; Cu: ≤0.001%; Hg: ≤0.0001%; Pb: ≤0.0002%; Zn: ≤0.001%; heavy metals (as Pb): ≤0.0010%
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+
• InChI key: WSWCOQWTEOXDQX-MQQKCMAXSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sorbic acid is commonly used as a preservative in pharmaceutical formulations and cosmetics. It is also used as additive for the preservation of food.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany