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Key Documents

870295P

Avanti

DSPE-RGD

Avanti Research - A Croda Brand 870295P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-(cysarginylglycylaspartate-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C68H120N9Na2O18PS
CAS Number:
Molecular Weight:
1460.75
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (870295P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870295P

application(s)

advanced drug delivery

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(C1CCC(CN2C(CC(SC[C@@H](C([O-])=O)NC([C@H](CC([O-])=O)NC(CNC([C@@H]([NH3+])CCCNC(N)=N)=O)=O)=O)C2=O)=O)CC1)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+].[Na+]

Biochem/physiol Actions

Arginine-glycine-aspartic acid (RGD) modified liposomes show potential for cancer research.

Packaging

5 mL Amber Glass Screw Cap Vial (870295P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available


Certificates of Analysis (COA)

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Cheng-Wei Chen et al.
International journal of nanomedicine, 6, 2567-2580 (2011-12-01)
Human retinal pigment epithelial cells are promising target sites for small interfering RNA (siRNA) that might be used for the prevention and/or treatment of choroidal neovascularization by inhibiting the expression of angiogenic factor; for example, by downregulating expression of the
Yunjie Cao et al.
International journal of clinical and experimental medicine, 8(8), 12182-12191 (2015-11-10)
In this study, we report an active targeting liposomal formulation directed by a novel peptide (RGD) that specifically binds to the integrins receptors overexpressed on prostatic cancer cells. The objectives of this study were to evaluate the in vitro and

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