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860400P

Avanti

14:0 PS-d54

Avanti Research™ - A Croda Brand 860400P, powder

Synonym(s):

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C34H11NO10PNaD54
CAS Number:
327178-93-8
Molecular Weight:
756.18
UNSPSC Code:
12352100
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860400P-10mg)
pkg of 1 × 25 mg (860400P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860400P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])C([2H]

General description

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (14:0 PS-d54) is a deuterated phosphoserine (PS) wherein 54 protons of dimyristoyl are replaced by deuterium.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (14:0 PS-d54) has been used to interact with lipid A to study the unspecific interaction of a phospholipid membrane with endotoxins. It has also been used as an apolar lipid internal standard for mass spectrometry.

Packaging

5 mL Amber Glass Screw Cap Vial (860400P-10mg)
5 mL Amber Glass Screw Cap Vial (860400P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipopolysaccharide-binding protein-mediated interaction of lipid A from different origin with phospholipid membranes Invited Lecture
Gutsmann T, et al.
Physical Chemistry Chemical Physics, 2(20), 4521-4528 (2000)
Dominique Mias-Lucquin et al.
Journal of structural biology, 209(1), 107411-107411 (2019-11-07)
Dystrophin is a large intracellular protein that prevents sarcolemmal ruptures by providing a mechanical link between the intracellular actin cytoskeleton and the transmembrane dystroglycan complex. Dystrophin deficiency leads to the severe muscle wasting disease Duchenne Muscular Dystrophy and the milder
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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