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Key Documents

850759C

Avanti

16:0-20:4 PE

1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine, chloroform

Synonym(s):

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; PAPE; PE(16:0/20:4(5Z,8Z,11Z,14Z)); 110638

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About This Item

Empirical Formula (Hill Notation):
C41H74NO8P
CAS Number:
Molecular Weight:
740.00
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 2.5 mL (850759C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850759C

concentration

10 mg/mL (850759C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

Application

16:0-20:4 PE has been used to determine its effect on oxidative burst in neutrophil granulocytes. It has also been used to determine its detergent solubility with equimolar concentration of sphingomyelin/cholesterol (SM/CHOL).

Packaging

5 mL Clear Glass Sealed Ampule (850759C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


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The oxidation state of phospholipids controls the oxidative burst in neutrophil granulocytes
Bluml S, et al.
Journal of Immunology, 181(6), 4347-4353 (2008)
Acyl chain unsaturation in PEs modulates phase separation from lipid raft molecules
Shaikh SR, et al.
Biochemical and Biophysical Research Communications, 311(3), 793-796 (2003)

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