850697C

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, chloroform

• Synonym(s): PE(6:0/6:0)
• Empirical Formula (Hill Notation): C₁₇H₃₄NO₈P
• CAS Number: 96893-06-0
• Molecular Weight: 411.43
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850697C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850697C
• concentration: 10 mg/mL (850697C-25mg)
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O

Description

General description

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) is a phosphoethanolamine (PE) molecule which carries short acyl chains. It is an ethanolamine-type substrate and a water-soluble phospholipid.

Application

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:

• as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity studies as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
• as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
• as calibration standard in hydrophilic interaction liquid chromatography (HILIC) and ion mobility (IM)

Biochem/physiol Actions

Phosphoethanolamine (PE) is known to possess antitumor activity and inhibitory effects on tumor progression in vivo. It also exhibits antiproliferative and proapoptotic effects. It acts as a precursor of phosphatidylcholine and phosphatidylethanolamine.

Packaging

5 mL Clear Glass Sealed Ampule (850697C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• wgk_germany: WGK 3