850144P

18:0-20:4 PI

Avanti Research^™ - A Croda Brand

• Synonym(s): 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); SAPI; PI(18:0/20:4(5Z,8Z,11Z,14Z)); 110661
• Empirical Formula (Hill Notation): C₄₇H₈₆NO₁₃P
• CAS Number: 1331751-28-0
• Molecular Weight: 904.16
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (ammonium salt)
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850144P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850144P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP(OC[C@H](OC([C19H31])=O)COC(CCCCCCCCCCCCCCCCC)=O)([O-])=O.[NH4+]

Description

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:0-20:4 PI or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (ammonium salt) has been used:

• as a negative control to evaluate the specificity of the interaction between cholesterol sulfate and receptor Mincle by surface plasmon resonance (SPR) experiment
• as a test lipid in liposomes harboring candidate triggering receptor expressed on myeloid cells 2 (TREM2) ligands, to assess TREM2 stimulation
• as a reference in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis to identify PI(18:0/20:4) in cancer tissue-originated spheroids (CTOSs) extraction

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850144P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850144P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids