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850141P

Avanti

16:0 PI

1,2-dipalmitoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/16:0); DPPI; 110657

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About This Item

Empirical Formula (Hill Notation):
C41H82NO13P
CAS Number:
34290-57-8
Molecular Weight:
828.06
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850141P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850141P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850141P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PtdIns) is a structural phospholipid. PI is synthesized by mycobacteria and other bacterial genera in prokaryotes.

Application

16:0 PI has been used as internal lipid standard for matrix-assisted laser desorption/ionization (MALDI)- fourier-transform ion cyclotron resonance (FTICR)- mass spectrometry (MS) and analysis. It is also suitable for use as an internal standard for mass spectrometric analyses.

Biochem/physiol Actions

Phosphatidylinositol (PI) participates in polyphosphoinositide turnover. It can be used as a substrate to produce several molecules, that can modulate various cellular functions. In eukaryotes, phosphatidylinositol (PI)-based lipids (phosphoinositides) plays a key role in intracellular signalling. It is also involved in the anchoring of glycosylphosphatidylinositol-linked proteins to the membrane.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850141P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850141P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Hanninen S, et al.
Bio-protocol, 7(9) (2017)
Phosphatidylinositol Turnover and Receptors
reference module in biomedical sciences (2016)
Phosphatidylinositol 4-Kinase from Bovine Brain
Methods in Neurosciences, 18, 93-99 (1993)
Jakub Suchodolski et al.
Yeast (Chichester, England), 37(1), 117-129 (2019-12-12)
Adherence of the fungus, Candida albicans, to biotic (e.g. human tissues) and abiotic (e.g. catheters) surfaces can lead to emergence of opportunistic infections in humans. The process of adhesion and further biofilm development depends, in part, on cell surface hydrophobicity
Structural basis for phosphatidylinositol-phosphate biosynthesis
Clarke OB, et al.
Nature Communications, 6, 8505-8505 (2015)
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