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Key Documents

330729P

Avanti

C15 Glucosyl(β) Ceramide-d7 (d18:1-D7/15:0)

Avanti Research - A Croda Brand

Synonym(s):

D-glucosyl-β-1,1′-N-pentadecanoyl-D-erythro-sphingosine-d7

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About This Item

Empirical Formula (Hill Notation):
C39H68D7NO8
CAS Number:
Molecular Weight:
693.06
UNSPSC Code:
12352211
NACRES:
NA.12

assay

99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (330729P-1MG)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])(O)[C@@]([H])(NC(CCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

General description

C15 Glucosyl(β) Ceramide-d7 (d18:1-D7/15:0) is a deuterated derivative of C15 Glucosyl(β) Ceramide. β-Glucosyl ceramide (β-GlcCer) is an intracellular metabolite. It is the first intermediate in the synthesis of glycosphigolipids. β-GlcCer is an endogenous ligand of Mincle.

Biochem/physiol Actions

β-Glucosyl ceramide (β-GlcCer) exhibits immunostimulatory activity. Accumulation of β-GlcCer is associated with Gaucher disease.

Packaging

5 mL Amber Glass Screw Cap Vial

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Intracellular metabolite beta-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity
Nagata M, et al.
Proceedings of the National Academy of Sciences of the USA, 114(16), E3285-E3294 (2017)

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