W318000

2-Mercaptopropionic acid

≥95%, FG

• Synonym(s): Thiolactic acid, 2-Mercaptopropionic acid
• Linear Formula: CH₃CH(SH)COOH
• CAS Number: 79-42-5
• Molecular Weight: 106.14
• FEMA Number: 3180
• Beilstein/REAXYS Number: 506218
• EC Number: 201-206-5
• Council of Europe no.: 4156
• MDL number: MFCD00004862
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901535
• Flavis number: 12.039
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 872/2012
• assay: ≥95%
• refractive index: n20/D 1.481 (lit.)
• bp: 102 °C/16 mmHg (lit.); 203-208 °C (lit.)
• mp: 10-14 °C (lit.)
• density: 1.196 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• organoleptic: meaty; roasted; sulfurous
• SMILES string: CC(S)C(O)=O
• InChI: 1S/C3H6O2S/c1-2(6)3(4)5/h2,6H,1H3,(H,4,5)
• InChI key: PMNLUUOXGOOLSP-UHFFFAOYSA-N

Description

General description

2-Mercaptopropionic acid is a synthetic flavor and skin sensitizer used in cosmetics, food and household care products.

Application

• Improving the Efficacy of ALA-Based Photodynamic Therapy: 2-MPA was used in the one-step aqueous synthesis of anionic and cationic AgInS2 quantum dots, demonstrating a significant enhancement in the therapeutic efficacy of aminolevulinic acid-based photodynamic cancer therapy (Hashemkhani et al., 2022).


• Fabrication of Hierarchical Core-Shell Heteroarchitectures: 2-MPA facilitates the assembly of Au@ZnO heterostructures for photocatalytic applications, underscoring its pivotal role in the synthesis of complex nanostructured materials (Pączkowski & Gawdzik, 2021).


• Investigating Genotoxic and Apoptotic Pathways: This study uses 2-MPA coated silver sulfide quantum dots to explore their effects on genotoxic and apoptotic pathways in vitro, providing insights into the biocompatibility and safety profile of these nanomaterials (Ozkan Vardar et al., 2018).

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 1
• flash_point_f: 190.4 °F - closed cup
• flash_point_c: 88 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter