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S4007

Sigma-Aldrich

Sodium iodate

≥99%

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About This Item

Linear Formula:
NaIO3
CAS Number:
7681-55-2
Molecular Weight:
197.89
EC Number:
231-672-5
MDL number:
MFCD00003533
UNSPSC Code:
12352302
PubChem Substance ID:
57654615
NACRES:
NA.22

Quality Level

100

assay

≥99%

density

4.28 g/mL at 25 °C (lit.)

SMILES string

[Na+].[O-]I(=O)=O

InChI

1S/HIO3.Na/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1

InChI key

WTCBONOLBHEDIL-UHFFFAOYSA-M

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Application

Sodium iodate (NaIO3) can be used as an oxidant in the following processes:     
  • NaIO3/neutral Al2O3 catalytic system is used to synthesize a variety of aromatic, aliphatic, and alicyclic disulfides via oxidation of the corresponding thiols.      
  • NaIO3/Na2SO3/HCl is used in the preparation of 2-amino-1-iodonaphthalene by iodination of 2-naphthylamine.
  • NaIO3/acetic anhydride or glacial acetic acid is used in aromatic oxidative iodination reactions.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Ox. Sol. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

5.1B - Oxidizing hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

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Simple Oxidation of Thiols with Sodium Iodate under Solid-Solution Biphasic Conditions
Hirano M, et al.
Journal of chemical research. Synopses, (12), 816-817 (1998)
Iodination of both deactivated and activated arenes with sodium periodate or sodium iodate as the oxidants
Lulinski P and Skulski L
Bulletin of the Chemical Society of Japan, 73(4), 951-956 (2000)
Brianna M Young et al.
Molecular therapy. Methods & clinical development, 14, 113-125 (2019-07-25)
Age-related macular degeneration (AMD) has been linked to oxidative damage and para-inflammation, an activation of inflammasome signaling in the retinal pigment epithelium (RPE) and the underlying choriocapillaris. Herein, we tested the efficacy of a gene-delivered caspase-1 inhibitor in controlling the
Huiming Xia et al.
Experimental eye research, 93(6), 862-872 (2011-10-13)
Regenerative medicine holds the promise of restoring cells and tissues that are destroyed in human disease, including degenerative eye disorders. However, development of this approach in the eye has been limited by a lack of animal models that show robust
M H Cao et al.
Journal of hazardous materials, 179(1-3), 1143-1146 (2010-04-21)
The photochemical decomposition of perfluorooctanoic acid (PFOA) in aqueous periodate (IO(4)(-)) was investigated under two types of low-pressure mercury lamps: one emits at 254nm light (UV light) and the other emits both 254 nm and 185 nm light (VUV light).
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