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Key Documents

QBD10785

Sigma-Aldrich

Biotin-dPEG®23-MAL

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C65H119N5O28S
Molecular Weight:
1450.72
UNSPSC Code:
12352200
PubChem Substance ID:

assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reactivity: thiol reactive

reagent type: cross-linking reagent

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN3C(C=CC3=O)=O)=O

Features and Benefits

Biotin-dPEG®23-MAL takes advantage of the well-known, specific Michael reaction between a maleimide group and a free sulfhydryl to allow site-specific biotin labeling of molecules in aqueous media within the pH range of 6.5 – 7.5. The single molecular weight dPEG® spacer (94.1 Å) provide precise spacing between the biotin moiety and the labeled molecule. The dPEG® spacer imparts water solubility to the labeled molecule while reducing immunogenicity, aggregation, and precipitation of labeled biomolecules or other labeled compounds.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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