P62003

2-Pyridinecarboxaldehyde

99%

• Synonym(s): Picolinaldehyde, Pyridine-2-aldehyde
• Empirical Formula (Hill Notation): C₆H₅NO
• CAS Number: 1121-60-4
• Molecular Weight: 107.11
• Beilstein/REAXYS Number: 105341
• EC Number: 214-333-6
• MDL number: MFCD00006290
• UNSPSC Code: 12352100
• PubChem Substance ID: 24898654
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 99%
• refractive index: n20/D 1.536 (lit.)
• bp: 181 °C (lit.)
• density: 1.126 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: [H]C(=O)c1ccccn1
• InChI: 1S/C6H5NO/c8-5-6-3-1-2-4-7-6/h1-5H
• InChI key: CSDSSGBPEUDDEE-UHFFFAOYSA-N

Description

Application

2-Pyridinecarboxaldehyde has been used:

• To synthesize chitosan based bifunctionalized adsorbent.
• In the aldol addition reaction with pyruvate in the presence of 2-keto-3-deoxy-6-phosphogluconate aldolase (KDPG) catalyst to form (S)-4-hydroxy-2-keto-4-(2′-pyridyl)butyrate.
• In the condensation reaction with (S)-(−)-α-methylbenzylamine and (R)-(+)-α-methylbenzylamine to synthesize two chiral (S)-(−)- and (R)-(+)Schiff base compounds.

It can also be combined with thiosemicarbazide to form 2-pyridinecarboxaldehyde thiosemicarbazone ligand (L) which can further complex with Ni(II) and Cu(II) salts (MX) to form [M(L)₂X₂] complexes.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H302,H314,H317,H330
• pcodes: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 2
• flash_point_f: 170.6 °F
• flash_point_c: 77 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter