P28263

2-Phenylphenol

99%

• Synonym(s): 2-Hydroxybiphenyl
• Linear Formula: C₆H₅C₆H₄OH
• CAS Number: 90-43-7
• Molecular Weight: 170.21
• Beilstein/REAXYS Number: 606907
• EC Number: 201-993-5
• MDL number: MFCD00002208
• UNSPSC Code: 12352100
• PubChem Substance ID: 24898365
• NACRES: NA.22

Properties

• vapor pressure: 7 mmHg ( 140 °C)
• Quality Level: 200
• assay: 99%
• form: solid
• bp: 282 °C (lit.)
• mp: 57-59 °C (lit.)
• fluorescence: λ_ex 231 nm; λ_em 356 nm
• SMILES string: Oc1ccccc1-c2ccccc2
• InChI: 1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
• InChI key: LLEMOWNGBBNAJR-UHFFFAOYSA-N

Description

General description

2-Phenylphenol, also known as o-phenylphenol, is commonly used as a chemical intermediate for the synthesis of pharmaceuticals, dyes, and fragrances.

Application

2-Phenylphenol can be used as a precursor in the synthesis of:

• Dibenzofurans via palladium-catalyzed, phenol-directed C-H activation/C-O cyclization or copper-catalyzed aerobic C-H activation, followed by cycloetherification.
• 6H-Dibenzo[b,d]pyran-6-ones via ruthenium-catalyzed carbonylative C-H cyclization.
• o-Phenylenes, a class of conjugated oligomers via an iterative sequence of Suzuki-Miyaura coupling reactions.
• o,o,p-Oligophenylenes via palladium-catalyzed C-H arylation.

Safety Information

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H315,H318,H335,H410
• pcodes: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 255.2 °F - closed cup
• flash_point_c: 124 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves