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Key Documents

M625

Sigma-Aldrich

Maleic anhydride

powder, 95%

Synonym(s):

2,5-Furandione

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About This Item

Empirical Formula (Hill Notation):
C4H2O3
CAS Number:
Molecular Weight:
98.06
Beilstein/REAXYS Number:
106909
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

3.4 (vs air)

vapor pressure

0.16 mmHg ( 20 °C)

assay

95%

form

powder

autoignition temp.

870 °F

expl. lim.

7.1 %

impurities

<5% maleic acid

bp

200 °C (lit.)

mp

51-56 °C (lit.)

SMILES string

O=C1OC(=O)C=C1

InChI

1S/C4H2O3/c5-3-1-2-4(6)7-3/h1-2H

InChI key

FPYJFEHAWHCUMM-UHFFFAOYSA-N

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1A - STOT RE 1 Inhalation

target_organs

Respiratory system

supp_hazards

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

217.4 °F - closed cup

flash_point_c

103 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Veronica H Flood et al.
Blood, 125(14), 2297-2304 (2015-02-11)
Von Willebrand factor (VWF) contains binding sites for platelets and for vascular collagens to facilitate clot formation at sites of injury. Although previous work has shown that VWF can bind type IV collagen (collagen 4), little characterization of this interaction
Emmanuel J Favaloro et al.
Thrombosis research, 134(6), 1292-1300 (2014-10-11)
von Willebrand disease (VWD) is reportedly the most common bleeding disorder and arises from deficiency and/or defects of von Willebrand factor (VWF). Laboratory diagnosis and typing has important management implications and requires a wide range of tests, including VWF activity
Ana Martinez et al.
Journal of medicinal chemistry, 48(23), 7103-7112 (2005-11-11)
The 2,4-disubstituted thiadiazolidinones (TDZD) are described as the first ATP-noncompetitive GSK-3 inhibitors. Following an SAR study about TDZD, different structural modifications in the heterocyclic ring aimed to test the influence of each heteroatom on the biological study are here reported
Glenn B S Miller et al.
European journal of mass spectrometry (Chichester, England), 21(3), 545-556 (2015-08-27)
We have conducted collision induced dissociation experiments on the hydrogen maleate anion (MaH(-), m/z = 115) and the anionic maleate MgCl complex (MaMgC(-), m/z = 173). In addition, we have computationally investigated the observed fragmentation reactions. We find that both
Neha N Parayath et al.
International journal of nanomedicine, 10, 4653-4667 (2015-08-01)
Drug delivery systems could potentially overcome low bioavailability and gastrointestinal toxicity, which are the major challenges for the development of oral anticancer drugs. Herein, we demonstrate the ability of styrene maleic acid (SMA) nanomicelles encapsulating epirubicin to traverse in vitro

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