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Key Documents

ALD01670

Sigma-Aldrich

3-methyl-3-((4-(trifluoromethyl)phenyl)amino)butan-1-ol

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About This Item

MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form

oil

storage temp.

2-8°C

SMILES string

CC(C)(CCO)NC1=CC=C(C(F)(F)F)C=C1

InChI

1S/C12H16F3NO/c1-11(2,7-8-17)16-10-5-3-9(4-6-10)12(13,14)15/h3-6,16-17H,7-8H2,1-2H3

InChI key

VOUKLDFTSAELPS-UHFFFAOYSA-N

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Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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