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ALD00578

Sigma-Aldrich

2-Bromopyridin-3-yl sulfurofluoridate

95%

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About This Item

Empirical Formula (Hill Notation):
C5H3BrFNO3S
Molecular Weight:
256.05
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

form

liquid

refractive index

n20/D 1.5160

transition temp

flash point >230 °F

density

1.8283 g/mL

storage temp.

2-8°C

Application

2-Bromopyridin-3-yl sulfurofluoridate can be used in the Pd-catalyzed Suzuki-Miyuara cross-coupling reaction. The fluorosulfate functionality was shown by Sharpless and coworkers to have distinct reactivity in comparison to other functional groups used in Suzuki-Miyuara reactions, such as bromides, chlorides and triflates. This inherent property provides a strong potential for selective Suzuki-Miyuara couplings for chemoselective reaction sequences.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3


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